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 yrTShanghai Natural Bio-engineering Co., Ltd
product name Coenzyme Q10
CAS number 303-98-0
Synonyms CoQ10,Ubiquinone, ubidecarenone, coenzyme Q, CoQ, Q10
Appearance Yellow powder
Specification 99%
Molecular formula (MF) C59H90O4
Molecular Weight (MW) 863.34
Solubility insoluble in water, oil-soluble
Dosage 30mg to 90mg
Main benefits Reduce high blood pressure, antioxidants, treat heart failure, Parkinson's disease
Applied industries supplements, cosmetics,pharmaceuticals

What is Coenzyme Q10?

Coenzyme Q10, according to Wikipedia, is a vitamin-like substance that is made naturally in in every cell of the body. Your body makes Coenzyme Q10, and your cells use it to produce energy your body needs for cell growth and maintenance. It also functions as an antioxidant, which protects the body from damage caused by harmful moleculesThe Q and the 10 in coenzyme Q10 refer to the groups of chemicals that make up the coenzyme, and Q refers to the quinone chemical group, and 10 refers to the number of isoprenyl chemical subunits in its tail.yrTShanghai Natural Bio-engineering Co., Ltd Coenzyme Q10 is also known by many other names such as CoQ10,Ubiquinone, ubidecarenone, coenzyme Q, CoQ, Q10, Vitamin Q10, but especially in the heart, liver, kidney, and pancreas.  Coenzymes help enzymes work to digest food and perform other body processes, and they help protect the heart and skeletal muscles.yrTShanghai Natural Bio-engineering Co., Ltd Enzymes help convert food into absorbable nutrients, and they help start the energy creation process in the cells. A "coenzyme", as a trigger or catalyst, is something that helps to make all these enzymes work. Coenzyme Q10 is now regarded as the most important of these coenzymes. This has become an important issue because many people in poor health or lacking in energy are found to have low levels of Coenzyme Q10.yrTShanghai Natural Bio-engineering Co., Ltd

Dietary Sources

Coenzyme Q10 is naturally present in small amounts in a wide variety of foods, but levels are particularly high in organ meats such as heart, liver, and kidney, as well as beef, soy oil, sardines, mackerel, and peanuts. Primary dietary sources of Coenzyme Q10 include oily fish (such as salmon and tuna), organ meats (such as liver), and whole grains. Most people get enough Coenzyme Q10 through a balanced diet, but supplements may help people with particular health conditions or those taking certain medications.yrTShanghai Natural Bio-engineering Co., Ltd

How Coenzyme Q10 works (mechanism of action)

Coenzyme Q10 (CoQ10) is a fat-soluble compound primarily found in your mitochondria, or the energy-producing organelles within your cells. CoQ10 is alternately called ubiquinone because of its ubiquitous presence and its quinone biochemical structure. yrTShanghai Natural Bio-engineering Co., Ltd Coenzyme Q10 works foremost in every cell of your body to synthesize energy. In your cells' mitochondria, CoQ10 helps generate adenosine triphosphate (ATP), your body's energy currency. It makes sense that organs with the highest energy needs - including the heart, liver, and kidneys - contain large amounts of CoQ10. yrTShanghai Natural Bio-engineering Co., Ltd Think of Coenzyme Q10 as an award-winning actor who can contribute dual performances in a show with equal aplomb. CoQ10 generates energy in its oxidized form, called ubiquinone. But it can quickly change costumes to ubiquinol, its reduced form, and act as a powerful antioxidant. yrTShanghai Natural Bio-engineering Co., Ltd Among its roles, ubiquinol protects fats, protein, low-density lipoprotein (LDL, a cholesterol transporter), and DNA from oxidative damage. It also regenerates vitamin E, another powerful antioxidant. yrTShanghai Natural Bio-engineering Co., Ltd

Benefits of taking Coenzyme Q10 supplements

As an over-the-counter nutritional supplement, CoQ10 has been used to treat many things, from heart disease, high blood pressure and high cholesterol to diabetes, breast cancer and gum disease. But that's not all. CoQ10 supposedly can help with immune deficiencies, increase fertility, treat Alzheimer's and Parkinson's, reduce ringing in the ears, delay aging and improve skin, and increase athleticism,etc.The key benefits of coenzyme Q10 are summarized as below:yrTShanghai Natural Bio-engineering Co., Ltd

1.Coenzyme Q10  and high blood pressure benefits

Currently, however, CoQ10 has shown the most definitive benefits in treating hypertension, or high blood pressure. People with high blood pressure have been shown to have less CoQ10 than normal, and CoQ10 has been shown to reduce blood pressure in early research.yrTShanghai Natural Bio-engineering Co., Ltd

2. Coenzyme Q10 and the Heart diseases benefits

People with heart failure have been found to have lower levels of Coenzyme Q10 in heart muscle cells. Double-blind research suggests that CoQ10 may reduce symptoms related to heart failure, such as shortness of breath, difficulty sleeping, and swelling. CoQ10 is thought to increase energy production in the heart muscle, increasing the strength of the pumping action. Several small trials have found CoQ10 may be helpful for certain types of cardiomyopathy.yrTShanghai Natural Bio-engineering Co., Ltd

3. CoQ10 and anti-aging benefits

The antioxidant power of CoQ10 also makes it an excellent natural anti-aging solution. Free radicals are destroyed, energy and vitality is increased and cells are brought back to a stable, healthy condition that might have been lost during mid-life. According to a published scientific study CoQ10 prevents skeletal decline by improving communication between genes and cells in the body.yrTShanghai Natural Bio-engineering Co., Ltd

4.Coenzyme Q10 and anti-cancer benefits.

Coenzyme Q10's antioxidant activity has led to suggestions that it might be beneficial in the treatment of cancer. In one 1994 study by Lockwood, none of the patients in the supplemented group died, versus the predicted or expected mortality of four; none had further metastases; and six showed apparent partial remission. Some people have also used coenzyme Q-10 for strengthening the immune systems of people with HIV/AIDS, male infertility, migraine headache, and counteracting muscle pain sometimes caused by a group of cholesterol-lowering medications called “statins.” yrTShanghai Natural Bio-engineering Co., Ltd

5. Coenzyme Q10 and Diabetes benefits

In a 12-week randomized controlled trial, 74 people with type 2 diabetes were randomized to receive either 100 mg CoQ10 twice daily, 200 mg per day of fenofibrate (a lipid regulating drug), both or neither for 12 weeks. CoQ10 supplementation significantly improved blood pressure and glycemic control.yrTShanghai Natural Bio-engineering Co., Ltd

6. Coenzyme Q10 and Parkinson's disease benefits

Lower levels of CoQ10 have also been observed in people with Parkinson's disease. Preliminary research has found that increasing CoQ10 may increase levels of the neurotransmitter dopamine, which is thought to be lowered in people with Parkinson's disease. It has also been suggested that CoQ10 might protect brain cells from damage by free radicals.yrTShanghai Natural Bio-engineering Co., Ltd A small, randomized controlled trial examined the use of 360 mg CoQ10 or a placebo in 28 treated and stable Parkinson's disease patients. After 4 weeks, CoQ10 provided a mild but significant significant mild improvement in early Parkinson's symptoms and significantly improved performance in visual function.yrTShanghai Natural Bio-engineering Co., Ltd

7. Coenzyme Q10 and its antioxidant benefits

As an antioxidant, Coenzyme Q10 helps protect your body against the harmful effects of toxins and also aids the absorption of beneficial vitamins and minerals.  Antioxidants are sometimes credited with boosting weight loss, possibly due to their energising effect on the body helping increase the fat-burning benefits of exercise.yrTShanghai Natural Bio-engineering Co., Ltd

Side Effects of taking Coenzyme Q10 supplements

Even though Coenzyme Q10 is a supplement and occurs naturally in your body, it doesn't mean that it's side effect free. However, most CoQ10 side effects are mild. Some people may experience allergies to increased Coenzyme Q10. There have been some reports of rashes and itching.yrTShanghai Natural Bio-engineering Co., Ltd Other side effects include a lowering of blood sugar within the body. This is particularly a concern for those with diabetes or hypoglycemia. In addition, if you're taking another medicine to regulate blood sugar levels, tell your doctor.yrTShanghai Natural Bio-engineering Co., Ltd

Dosage of taking Coenzyme Q10 supplements

How much CoQ10 should you take? Depends on what you use it for. As we have mentioned before, there are at least seven key benefits for taking coenzyme Q10, and for each different purpose, the dosage differs. A good maintenance dose for a healthy person would be 60 mg a day. Other doses range from 30 mg (for mild congestive heart failure) to 1,200 mg (progression of Parkinson disease). A typical CoQ10 dosage is 30 to 90 mg per day, taken in divided doses, but the recommended amount can be as high as 200 mg per day.yrTShanghai Natural Bio-engineering Co., Ltd Shanghai Natural Bio-engineering Co., Ltd, established in 2003, is a professional large-scale high-tech manufacturer of raw materials for nutraceuticals, nutritional supplements, and pharmaceuticals, and plant extracts, Active Pharmaceutical Ingredient (API) & intermediates are our focused areas. Bulk raw materials for Coenzyme Q10 are available directly from inventories.  yrTShanghai Natural Bio-engineering Co., Ltd

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